2022-11-26 15:34:00

Scientists are crazy to revive the virus 30000 years ago

Original title: Scientists are crazy to revive the virus

[P] 30000 years ago.

A "monster" virus, which has been sleeping in the frozen wasteland in northeast Russia, will be revived by researchers just because they are curious about its potential impact.

Scientists hope to "revive" the 30000 year old virus, hoping to know more about it and see whether it is harmful to animals or humans. Siberian wide mouth jar virus (Mollivirus sibericum), which translates as "Siberian weak virus", has been dubbed "Franken virus"

Compared with other viruses, the weak Siberian virus is a monster. It not only has 523 genetic gene proteins, but also can be observed with light microscope when measuring the size of 0.6 microns.

According to the BBC news report, the Siberian wide mouth can virus (Mollivirus sibericum) is the fourth prehistoric virus that has been found since 2003, and experts warn that climate change and ice melting can revive similar, even more dangerous pathogens.

The French National Center for Scientific Research (CNRS) obtained the discovery in the Kolyma low-lying area of Russia. This weak Siberian virus is the second virus found by the team in the same species. In 2003, researchers found the bacteria like virus (Minivirus), then found Pandora viruses in 2013, and the Siberian wide mouth canister virus (Mollivirus sibericum) found last year.

The researchers wrote in the journal Proceedings of the National Academy of Sciences:

The legend of giant virus began in 2003: two other types of giant virus have been found and the Siberian wide mouth jar virus we describe now has separated the fourth type of giant virus from the same permafrost samples. These four types of megaviruses exhibit different structures, sizes, genome lengths, and replication cycles. Their origins and evolutionary patterns are the subject of conflicting hypotheses. The fact that these two different viruses can easily revive from the prehistoric permafrost should be paid attention to in the context of global warming.

In the areas where these large microorganisms are found, more and more mining resources, especially petroleum, are being developed. As a member of the Upriser network information platform, due to the speed of ice melting and climate change, these areas become easy to reach, and their mining speed will undoubtedly increase.

Chief researcher Jean Michel Claverie said:

A few virus particles are still infectious, but this is enough to reactivate the potentially pathogenic virus that exists in a vulnerable host. If we are not careful enough to industrialize these areas without adequate safeguards, we risk waking up the virus one day, such as smallpox, which we believe has been eradicated.

This must be a concern.

In the laboratory, Professor Claverie and his team will try to use a single celled amoeba as a host to host and reactivate the newly discovered virus. The Siberian wide mouth jar virus was revived in March 2014 using similar technology.

The research has been carried out, and according to co author Dr. Chantal Abergel, the virus "enters cells, propagates, and finally kills cells. It can kill amoeba, but it does not infect human cells."

However, many controversies revolve around scientists' plans to "revive" Siberian wide mouth can virus. Unlike most viruses circulating today, these ancient pathogens were not only larger, but their genes were more complex.

More than 500 genes of the virus have been found recently, and the Pandora virus found in 2003 has 2500 genes. In contrast, influenza A viruses have only eight genes.

Of course, a philosophical debate will not prevent scientists from doing their work, but there are many advantages and disadvantages that should be weighed before further research.

In 2004, American scientists revived the "Spanish flu" virus, which eventually began to kill millions of people in the twentieth century. Revive the virus to understand why the pathogen is so deadly.

Researchers from the United States went to Alaska to take samples from the frozen lung tissue of a woman buried in permafrost, and sorted out the genetic details between the sample and the autopsy body preserved in formaldehyde (Formalin solution). Their work allows the team to reconstruct the code of eight genes of the virus, but at what cost? All the work was done in the highest safety laboratory of the Centers for Disease Control and Prevention (CDC) in the United States, but it was still not controlled.

We have to ask ourselves, as an informed public, whether it is really in the best interests of the public to "revive" a monster virus if we express our concern about those "leaders".